Located on beautiful Sanibel Island, Sweet Melissa’s Cafe offers a wide variety of unique flavorful dishes that are sure to please the palate. Chef Melissa Talmage offers nightly specials including sweetbreads, tuna carpaccio, to local favorite conch chowder! Our amazing wine list has been carefully selected to match Melissa's creations. Do wine pairings, wine flights, by the glass or just buy a bottle. We have a private dining room for large parties and also do party planning or catering! Full bar and outside seating make this restaurant a must for all foodies!